Fox has had recurring roles in the TV series Terries, in Gayle We Trust, Svetlana, Parks and Recreation, Who Gets the Last Laugh?, and Romantic Encounters with Melinda Hill. He has starred in the movies Wyatt Earp, In the Army Now, The Trigger Effect, Infinity, The Postman, Crazy in Alabama, Mumford, The Patriot, The Right Temptation, City of Ghosts, Pauly Shore is Dead, Forgetting Sarah Marshall, the Lodger, Post Grad, Let Go, and Any Day Now. Fox wrote the film Pauly Shore is Dead and co-produced the film Tennis, Anyone…?. As a stand-up comedian he appeared on the Tonight Show with Jay Leno and had a TV special Comedy Central Presents: Kirk Fox.